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Cafeina Cafe

Cafeina Cafe Cafeina Cafe is a coffee shop located on 46th Street in San Diego that prides itself on crafting quality drinks with natural ingredients. They offer a variety of beverages, including their popular Jamaica Lemon Lime made with in-house hibiscus and lemon syrup and topped with sparkling water. In addition to drinks, they also offer festive conchas every morning (while supplies last) and even have modern loose fit zip-ups available for purchase. Stop by Cafeina Cafe for a simple moment of relaxation and excellent coffee.

Recent social media posts

01/23/2026

☕️🍺COLLAB🍺☕️

Our first ever beer Collab with Starting TOMORROW you’ll be able to get your hands on our first English Porter Style Beer brewed by their very own brewer/janitor Hunter!

Thank you for the opportunity to create something fun and trying new methods of brewing with our coffee ☕️

*ONLY available at

01/19/2026

⏰ NEW SHOP HOURS⏰

☕️MONDAY-SATURDAY☕️
7am-4pm

☕️SUNDAY☕️
7am-4pm

More time to grab a coffee 🧡

✨HOLIDAY HOURS✨Christmas Eve7am-1pmChristmas Day7am-1pmNew Years eve7am-3pmNew years dayCLOSED🧡☕️
12/21/2025

✨HOLIDAY HOURS✨

Christmas Eve7am-1pmChristmas Day7am-1pm
New Years eve7am-3pmNew years dayCLOSED

🧡☕️

12/19/2025

💚 Green Tote Bags In Stock💚

Also check out our friends .flowers for any last minute gifts!

Also available online www.cafeinacafe.com

🎁✨Seasonal Drinks✨🎁 1. Gingerbread Latte w/ Peppermint Cold Foam 🎁2. Tres Leche Latte 🍰 3. Rompope Latte (Eggnog) ☕️All ...
12/16/2025

🎁✨Seasonal Drinks✨🎁

1. Gingerbread Latte w/ Peppermint Cold Foam 🎁
2. Tres Leche Latte 🍰
3. Rompope Latte (Eggnog) ☕️

All of our drinks are made from scratch using eggs, milk, real ginger, molasses, sugar. (Please let us know of any known allergies 🤧)

Limited batches made weekly as we try to keep up with demand! 🧡

📸 .visual

🪅Ven a pedirnos posada este Sabado, Diciembre 12.  Comunidad, comida, musica y diversión!!🪅  ✨️We will have Salvadorian ...
12/02/2025

🪅Ven a pedirnos posada este Sabado, Diciembre 12. Comunidad, comida, musica y diversión!!🪅
✨️We will have Salvadorian Tamles for sale🫔 We'll also be serving Pozole & Ponche or Rompope!☕️
✨️Crafts will be available for children and adults alike!
✨️ D.J will be bumping from 6pm-8pm🎧
✨️ Last but not least! We will be ending the night with a Piñata🪅 and 3 rounds of Lotteria! (Prizes for the winners!)🏆

☕️Team Post☕️for November, we all decided to grow out our mustaches just like Andrew 🥸 jk The reality of small business,...
11/28/2025

☕️Team Post☕️

for November, we all decided to grow out our mustaches just like Andrew 🥸 jk

The reality of small business, teams are like seasons it’s always ever changing, but the team now are building a core, that’s ever evolving, for what the future has in store for us 😉

AND we’re obviously thankful for YOU! To our day ones and new faces 😊 We’re thankful 365 days out of the year, able to keep our doors open to serve community, visitors coffee lovers 🧡☕️

☕️HOLIDAY HOURS☕️ Thanksgiving Day11.27 7AM-1PMBLACK FRIDAY11.28 7AM-3PMSMALL BUSINESS SATURDAY11.30 8am-3pm
11/26/2025

☕️HOLIDAY HOURS☕️

Thanksgiving Day
11.27 7AM-1PM
BLACK FRIDAY
11.28 7AM-3PM
SMALL BUSINESS SATURDAY
11.30 8am-3pm

Today’s  birthday! Tell him happy birthday when you come to Cafeina! 🫵🏽😡☺️ ♏️ Thank him in tips and good energy for bein...
11/21/2025

Today’s birthday! Tell him happy birthday when you come to Cafeina! 🫵🏽😡☺️ ♏️ Thank him in tips and good energy for being a great barista ☺️

🔥Overdue post!🔥We want to extend a huge thank you to .coffee.roasters. It all started at a coffee cupping table, the res...
11/18/2025

🔥Overdue post!🔥

We want to extend a huge thank you to .coffee.roasters. It all started at a coffee cupping table, the rest is history. Luis opened his door to us 2 years ago when were ready to start our roasting journey. Without hesitation, he gave us a space and the tools we needed to start. We roasted A LOT of bad coffee! Eventually we managed to dial in our craft. Spaces like this deserve more attention, for Luis and his team care about the craft. We took a bit of that knowledge with us that he kindly shared without holding back any “secrets”. The secret is that we have our own styles, and no style is “better” than another. Oh and don’t forget to say hi to Trapo!

We also want to give a shoutout to Cano .co for his mentorship! 🤝🏽🔥

Coffee journey/story to be continued…

A love letter 💌
02/14/2025

A love letter 💌

Address

4011 46th Street
San Diego, CA
92105

To get to the location at 46th Street in San Diego using public transportation, you can take bus number 7 and get off at the corner of 46th and El Cajon Blvd. If you prefer to drive, there is street parking available on 46th Street and nearby side streets. Please note that parking restrictions may apply during peak hours.

Opening Hours

Monday 7am - 3pm
Tuesday 7am - 3pm
Wednesday 7am - 3pm
Thursday 7am - 3pm
Friday 7am - 3pm
Saturday 7am - 3pm
Sunday 7am - 3pm

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What people say

Cafeina Cafe on 46th Street in San Diego is a coffee shop that offers quality drinks made from natural ingredients. Their Jamaica Lemon Lime drink, made with their in-house hibiscus and lemon syrup, a squeeze of lime, and topped with sparkling water, is perfect for the San Diego weather. They also offer beautiful and festive conchas every morning while supplies last. Customers can place their orders ahead of time to ensure they get one to start their day off right. Cafeina Cafe also has new color ways available in the spirit of Valentine's month, including super soft, modern loose fit zip-ups perfect for the weather. The cafe appreciates its customers and encourages them to take a moment to reset and enjoy simple moments like taking the first sip of cafecito in the morning. Overall, Cafeina Cafe is a great spot for coffee lovers looking for quality drinks made from natural ingredients.

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